Ld50 Of Euphorbia Hirta Extract

Euphorbia Hirta

Attah et al. (2013) evaluated the ethanol extract of Euphorbia hirta to determine its effect against Onchocerca volvulus microfilariae. At the end of the study, it was found out that at different levels in vitro, Euphorbia hirta immobilized microfilariae.

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Evaluation of Antioxidant, Vitamins, Phytochemicals and …

The present paper reports contents of antioxidants, fat, protein, carbohydrate, fiber and minerals content in the leaves of medicinally important plant E. hirta Linn. collected from …

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LC50 of methanolic extract of Euphorbia hirta parts (values …

The median lethal dose (LD50) value is greater than 5000 mgkg⁻¹ body weight, with no significant change in bodyweight or relative organ weight (ROWs) of the extract-treated …

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(PDF) EUPHORBIA HIRTA LINN

LC50 of ethylacetate, acetone extract of Euphorbia hirta and methanol extract of Euphorbia. nerifolia Linn were found to be 71.15, 92.15 and 49.55µg/ml respectively. Among these two....

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Phytochemical profile of Euphorbia hirta plant extract and …

Recently, the plants-derived bioactive components received a greater interests due to their significant anti-carcinogenic properties. Euphorbia hirta is a well known herbal plant, which is highlighted to show a remarkable anticancer activities against several types of cancers. In this study, we analyzed the in vitro antitumor action of E. …

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Euphorbia hirta: Its chemistry, traditional and medicinal uses…

Lyophilised aqueous extract of Euphorbia hirta L. (Euphorbiaceae) has been evaluated for analgesic, antipyretic and anti-inflammatory properties in mice and rats, in order to complete its activity ...

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Evaluation of the Antioxidant, Anti-Inflammatory, and …

The concentration of the extract required to trap 50% of DPPH (IC 50) was 0.205 mg/mL. Online HPLC analysis of the extract also showed strong antioxidant …

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Acute and Subchronic Toxicity Study of Euphorbia hirta L.

According to the chemical labelling and classification of acute systemic toxicity recommended by OECD, the crude extract of E. hirta extract was assigned class …

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ANTIBACTERIAL ACTIVITIES AND TOXICOLOGICAL …

Based on the LD50 studies doses of 60.4mg/kg body weight, 120.8mg/kg body weight, 241.5mg/kg body weight and 483.0mg/kg body weight were injected into each group of the rats through the intraperitoneal route ... concentrations of crude ethanolic extract of Euphorbia hirta) ) and .

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(PDF) Potensi Tumbuhan Liar Patikan Kebo (Euphorbia hirta) …

LD50 diperkirakan lebih dari 5000mg/kg. Dalam ... Honey fortified with extract of Euphorbia hirta was designed as functional food to comply the practical uses and as health beneficial food ...

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Formulation, characteristics and anti-bacterial effects of Euphorbia

Each of the formulations of Euphorbia hirta L. mouthwash showed no significant differences in either the activity or preference tests. The ethanol extract of Euphorbia hirta L. had ideal physical and stability characteristics for mouthwash and anti-bacterial effects that neutralise Streptococcus mutans.

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Assessment of Euphorbia hirta L. Leaf, Flower, Stem and …

The antimicrobial activities of the methanolic extracts of Euphorbia hirta Lleaves, flowers, stems and roots were evaluated against some medically important bacteria and yeast using the agar disc diffusion method. Four Gram positive (Staphylococcus aureus, ...

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(PDF) Antiulcer Effects of Methanol Extract of Euphorbia hirta …

Antiulcer Effects of Methanol Extract of Euphorbia hirta and Honey Combination in Rats. November 2020; ... Acute toxicity studies showed that LD50 was greater than 5000 mg/kg. The study showed ...

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REVIEW ON PHYTOCHEMISTRY AND …

An aqueous extract significantly inhibited aflatoxin production on rice, wheat, maize and groundnut (27). Anti-platelet aggregation and anti-inflammatory: Aqueous extracts of Euphorbia hirta strongly reduced the release of prostaglandins I2, E2, and D2. Additionally Euphorbia hirta extracts exerted an inhibitory

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[PDF] Acute toxicity impacts of Euphorbia hirta L extract on …

E. hirta leaves methanol extract has exhibited mild toxic effects in mice and no significant statistical differences found between body weight, relative (%) and absolute organ weights of treated and untreated groups were found. Background: The methanol extract of Euphorbia hirta L (Euphorbiaceae), which is used in traditional medicines, …

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Euphorbia Hirta Extract | %(HPLC) | In Stock | Others inhibitor

Euphorbia Hirta Extract is extracted from Euphorbia Hirta, which is used in the treatment of gastrointestinal disorders. Quality confirmed by NMR & HPLC. See customer reviews, validations & product citations.

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Antimicrobial activity Euphorbia hirta ethanolic …

Antimicrobial activity Euphorbia hirta ethanolic extract Abubakar Muyibi1, ... (MIC) and minimum lethal concentration (MBC) of the extract were determined by serial dilution method.

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Euphorbia Hirta

The oral LD 50 of aqueous leaf extract in rats is >5000 ... 250, and 1000 mg/kg per day of Euphorbia hirta extract revealed no significant difference in consumption of food and water, weight change, hematological and biochemical parameters, relative organ weights compare to control group.

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Extracts of Euphorbia hirta Linn. (Euphorbiaceae) and …

Extracts from both plants possess antifilarial properties; however, the crude extract of E. hirta was found to be least toxic to LLCMK2. BackgroundOnchocerciasis transmitted by Onchocerca volvulus is the second major cause of blindness in the world and it impacts negatively on the socio-economic development of the communities affected. …

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Acute toxicity impacts of Euphorbia hirta L extract on …

Background: The methanol extract of Euphorbia hirta L (Euphorbiaceae), which is used in traditional medicines, was tested for in vivo toxicity. Materials and methods: In vivo brine shrimp lethality assay and oral acute toxicity study at single high dose of 5000 mg/kg and observation for 14 days in mice were used to study the toxic effect of E. hirta.

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Review on the phytochemistry, toxicology and bioactivities of Euphorbia

Euphorbia hirta L. extract on behavior, organs body weight index and histopathology of organs of the mice and Artemia salina . Pharmacognosy Res. 4(3):170-177. doi: 10.4103/097 4-8490.99085.

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Larvicidal Activity of Tawa-tawa (Euphorbia hirta) and …

Euphorbia hirta) and Oregano ... revealed that both leaf extract contains alkaloids and has no terpenoids. ... studies on dose analysis and lethal concentration may be considered to fully explore ...

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Antidiabetic activity of ethanolic extract of Euphorbia …

The LD 50 value of ethanolic extract of Euphorbia hirta Linn was calculated by using experimental data. A computer guided statistical program - AOT425statPgm was used for the determination of the LD 50 value. ... extract of Euphorbia hirta Linn (800 mg/kg) to glucose-fed rats induced time dependent hypoglycemic effect (Fig No 2) . ...

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determination of ld50 of euphorbia hirta.md

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The potential of young and old Euphorbia hirta leaves extract …

The potential of young and old Euphorbia hirta leaves extract as antibacterial against Escherichia coli and antihelminthic against Ascaridia galli obtained in Sentul chickens. Biodiversitas 23: ...

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Frontiers | Phytochemicals of Euphorbia hirta L. and Their …

Euphorbia hirta L. (Euphorbiaceae) is a medicinal plant widely used in the Philippines and across tropical Asia, and it is commonly known by the following names: "asthma plant" (English), "tawa-tawa" (Filipino), and "mangagaw" (Cebuano). The extract of E. hirta is taken

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Acute toxicity impacts of Euphorbia hirta L extract on …

LD 50 of more than 5000 mg/kg of E. hirta methanol leaves extract is an indication that the extract is safe. However, lethal effect being found in this test indicated that the methanol …

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Determination of LC50 values of extracts of Euphorbia

The results showed that the LC 50 of ethyl acetate and acetone extract of Euphorbia hirta were 71.15 and 92.15 ug/ml respectively [101].On the other hand, flavonol glycosides (afzelin, quercitrin ...

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(PDF) EUPHORBIA HIRTA LINN

Euphorbia hirta Linn. is a small herb, belongs to family Euphorbiaceae, distributed throughout the hotter part of India, often found in waste places along the roadsides.

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Antibacterial activities and toxicological potentials of …

Initial LD 50 studies carried out were used to determine the maximum dose that did not produce any death in rats. Four groups of albino ... Antibacterial screening of the different concentrations of crude ethanolic extract of Euphorbia hirta. Concentrations of Zones of inhibition (mm) extract (mg/ml) E. coli S. aureus P. aeruginosa B. subtilis ...

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Acute toxicity impacts of Euphorbia hirta L extract on …

Results: Brine shrimp lethality assay was used to calculate the median lethal concentration (LC (50)) of E. hirta (for leaves, stems, flowers and roots) methanolic …

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